Adele broke down in tears as she dedicated her gig to the Orlando shooting victims.
At least 50 people died and 53 were injured when a gunman opened fire inside gay nightclub Pulse over the weekend and the 27-year-old singer felt "really moved" by the tragedy.
After opening her show in Antwerp, Belgium, on Sunday (12.06.16) with 'Hello' and 'Hometown Glory', she said: "I'd like to start tonight by dedicating this entire show to everybody in Orlando, and at Pulse nightclub last night.
"The LGBTQI community... they're like my soulmates, since I was really young, so I'm really moved by it."
In March, Adele dedicated a performance in London to the victims of a terrorist attack in Brussels, Belgium, which saw 34 people killed and 250 injured when suicide bombers struck at an airport and a metro station, and urged her fans to sing for those affected by the tragedy.
She said on stage at the time: "We're all here for the same reason. I'm hoping you've all come to be entertained by me.
"I'm here to entertain you, so we're all united, so that makes us much better than them f***ers. You're on, you f***ers.
"'This is 'Make You Feel My Love' and this is for Brussels tonight.
"I want you to all sing it with me, alright, so they hear us."
After finishing the track, she was visibly moved and said: "I don't think I've ever actually been so moved before in my life at one of my shows, that was just so beautiful.
"Thank you very much for doing that... I think they heard us."
Model-and-actress Cara Delevingne was in the audience for the show and admitted the poignant tribute had made her cry.
She posted on Instagram: "I cried... a lot and laughed even more! A truly beautiful and inspiring show thank you @adele for being you! (sic)"