Vince Vaughn thinks it is "insane" that drugs are illegal.
The 'Wedding Crashers' star insists the world is in a "f***ing ridiculous" place because of the black market narcotic industry and doesn't believe everyone who uses illicit substances is "dangerous".
He said: "I look at the drug wars and they are absolutely f***ing ridiculous. There is a black market and the prisons are overcrowded and it's not preventing drug use.
"There's a corruption that goes all the way to the top.
"[Would I decriminalise drugs?] Yes of course. It's insane. I'm not saying that drugs can't be dangerous but not everyone that does drugs is going to go out and hurt somebody."
The 45-year-old actor believes "experimenting" with drugs is just a part of growing up.
Speaking about the early days of his career, he told Britain's GQ magazine: "I enjoy a few drinks and there was a stage back there where I realised I was going out and drinking until 2am five nights a week, but you grow out of that stuff.
"Just like experimenting with drugs, it's part of growing up, a choice that everyone has to make or not make. You realise what works or what doesn't work."